One of the most trusted and research backed supplement in the market is creatine. Not only is the supplement beneficial for the end-users, but also for the businesses manufacturing them. It’s market is rising rapidly and is forecasted to grow at a staggering value of $2.8 billion by 2030.
This blog post emphasizes on the various process that goes behind manufacturing creatine monohyhdrate. It is often seen as a non-vegetarian product scraped out of animals.
This post unpacks the full story, step-by-step, on what exactly is creating and the step-by-step creatine manufacturing process. Let’s break it down so you know exactly what’s fueling your next PR.
What Is Creatine Made of?
Creatine is a natural compound formed in our body, it is made of three amino acids which are L-arginine, glycine, and L-methionine.
The combination of these amino acids is called tripeptide, also known as creatine. Creatine plays an important role in cellular energy production. It is the most tested supplement out there when it comes to boosting performance during high-intensity activities such as sprinting or weightlifting.
Quick Facts about Creatine
- Human body is able to produce creatine, it synthesizes around 1 gram of creatine per day.
- Primary production of creatine takes place in liver, kidneys, and pancreas, afterwards it is stored in the muscle tissue.
- For enhanced performance and cellular energy production, the daily suggested intake of creatine is around 3-5 grams per day, which our body is not able to produce.
Naturally occurring creatine sources
Creatine is also present in certain animal-based foods, but not in practical quantities. Here's what you'd need to consume to reach optimal intake levels:
- Herring: You will need to take around 1.67-2.76 pounds to meet the daily requirement
- Pork: Almost 2.17-3.48 lbs of pork will be needed to meet the daily intake.
- Beef: 2.5-4 lbs of beef contains the amount of creatine required to meet your daily intake.
- Salmon: 2.5-4 lbs of salmon is required to meet the daily creatine intake.
- Cod: 3.5-5 lbs of salmon contains the amount of creatine needed by average healthy human.
Unless you’re aiming for a 10,000-calorie diet, food is not a viable source for hitting optimal creatine levels.
In short, creatine is made from amino acids, but to use it effectively, you’ll need more than your body or diet alone can provide. That’s where the creatine manufacturing process steps in.
How Is Creatine Manufactured? Step-by-Step Process
Extracting creatine from animals, or from plants is not a viable solution. Creatine is synthesized chemically, but the process is safe, pure and harmless.
Here’s a breakdown of the creatine production process, step by step:
Raw Material Selection
- Two most important elements in manufacturing creatine are sodium sarcosinate and cyanamide.
- Sodium sarcosinate is derived from glycine, that is involved in choline metabolism.
- Cyanamide is key reactant in the process, it is a safe industrial chemical. P.S.- Do not confuse Cyanamide with Cyanide.
Chemical Reaction & Crystallization
- To begin the chemical reaction, both the compounds are first put in a controlled reactor.
- Firstly, the a liquid intermediate is formed using high temperature and pressure on the mixture of sodium sarcosinate and cyanamide.
- After lowering the temperature, crystalline creatine starts to form.
Centrifugation & Purification
- Afterwards, the purification process begins through centrifugation.
- Any unwanted particles, residue are removed in this process before vacuum drying and milling.
Vacuum Drying & Milling
These pure creatine crystals are then vacuum dried, this process removes any moisture leftovers before milling. Milling process converts it into fine powder, around 200 mesh to maximize the solubility and absorption in the body.
Final Packaging
Your final product is now ready. This ultra-fine creatine monohydrate is now packaged to be dispatched to the market.
No blending or fillers are required, making it ideal for both bulk buyers and consumer-ready formulations. Before shipping, the product undergoes quality.
How Abha Biotechnology Powers Your Creatine Supplement Line?
Abha Bio isn’t just a supplier, we’re your full-scale third-party supplement manufacturing company.
- End-to-End Manufacturing: From sourcing to finished creatine monohydrate powder, capsules, or blends.
- GMP-Certified Facility: Built for compliance, consistency, and quality control at scale.
- Raw Material Expertise: Secure, high-grade sodium sarcosinate and cyanamide, with full traceability.
- Custom Formulations: Creatine + electrolytes? Creatine + BCAAs? We help you innovate.
- Fast Turnaround: R&D, sampling, and production, streamlined to get you to market faster.
Whether you're launching a new product or scaling an existing line, Abha Bio is built to make your creatine brand work harder.
Conclusion
Creatine isn’t just a white powder, it’s a precision compound built from amino acids, engineered for results.
You now know what your body can produce, what your diet can’t deliver, and how modern science fills that gap.
But here’s the real kicker:
The way creatine is made determines how well it works.
- If the raw materials aren’t clean, you get impurities.
- If the reaction isn’t controlled, you lose potency.
- If the crystals aren’t milled right, you sacrifice absorption.
Don’t settle for “just creatine.”
Whether you’re formulating for elite athletes or first-time lifters, choose creatine that’s certified, tested, and built for performance, not just shelf appeal.
FAQs
Q1: Is creatine natural or synthetic?
Creatine is a naturally occurring compound in the body, but supplemental creatine, like creatine monohydrate, is chemically synthesized from safe, lab-grade raw materials such as sodium sarcosinate and cyanamide.
Q2: What are the raw materials used to make creatine?
The two main ingredients in the creatine manufacturing process are sodium sarcosinate (derived from glycine) and cyanamide, a safe industrial compound often confused with cyanide (but entirely different).
Q3: Is creatine made from animals?
No. Despite common myths, creatine supplements are not derived from animals. They are synthesized through a controlled chemical reaction, making them suitable for vegans and vegetarians.
Q4: Is synthetic creatine safe to use?
Yes. Creatine monohydrate produced via chemical synthesis is safe, stable, and highly pure, especially when manufactured in GMP-certified facilities and tested for heavy metals, microbes, and impurities.